| abstract |
The present invention relates generally to compounds and chemicals that are effective against hepatitis C virus (HCV) infection. The present invention further includes compositions comprising said compounds and / or chemicals, methods for preventing HCV infection, and compounds for the preparation of compositions useful for the prevention and / or treatment of HCV infection and / or Regarding the use of chemical substances. Useful compounds and chemical entities of the present invention, the selenium, selenium salts, vitamin D 3 and retinoids, for example all-trans retinoic acid and its salts, C 1 -C 10 alkyl amides of all-trans retinoic acid and its salts, all trans retinoic C 1 -C 10 alkyl esters and their salts of acids, 9-cis retinoic acid and its salts, 9-cis C 1 -C 10 alkyl amides of retinoic acid and its salts, 9-cis C 1 -C 10 retinoic acid Alkyl esters and their salts, (E) -4- [2- (5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl-1-propenyl] benzoic acid (TTNPB) , (4- [5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl) carboxamide] benzoic acid (AM-580), N- (4-hydroxyphenyl) retinamide ( 4-HPR), and 6- [3- (1-adamantyl) -4-hydroxyphenyl] -2-naphthalenecarboxylic acid (AHPN). |