| abstract |
The present invention relates to methods of treatment by modulating peroxisome proliferator activated receptors by using compounds of structural formula I. The variable I is defined herein. Also included are compounds, methods for preparing the compounds and pharmaceutical compositions. The compounds of the present invention prevent X syndrome, type II diabetes, hyperglycemia, hyperlipidemia, obesity, clotting abnormalities, hypertension, atherosclerosis, and other disorders and cardiovascular diseases associated with X syndrome. It is believed to be effective in treating and preventing. |