| abstract |
The present invention relates to synthetic immunogenic lipopeptide molecules comprising co-linear epitopes of T helpers and B cells, methods for their production, use in generating primary and secondary immune responses, and vaccination of animal subjects against specific antigens. Provide use in. More specifically, the present invention relates to highly soluble lipopeptides in which the lipid moiety is attached to the terminal side chain group of an internal lysine or lysine analog, preferably the terminal side chain group of an internal diamino acid residue. I will provide a. Preferably, the internal lysine or lysine analog is located between or within the T helper epitope and B cell epitope. |