| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4525 |
| filingDate |
2002-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2006-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2006512278-A |
| titleOfInvention |
Process for producing paroxetine substantially free of alkoxy impurities |
| abstract |
The present invention relates to a method for producing an intermediate useful for synthesizing paroxetine substantially free of alkoxy impurities, and a method for producing paroxetine substantially free of alkoxy impurities and pharmaceutically acceptable salts thereof. By reacting the alkoxy impurity with an ether cleaving agent, the corresponding phenol is generated and the corresponding phenol is separated to yield the desired product substantially free of alkoxy impurities. Paroxetine intermediates substantially free of alkoxy impurities, such as PMA, paroxetine and pharmaceutically acceptable salts thereof also form part of the present invention. |
| priorityDate |
2001-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |