| abstract |
Trilayered or more multilayered tablets are provided that are useful for lowering cholesterol levels and reducing the risk of myocardial infarction. The tablet is preferably aspirin in the first layer, pravastatin in the other layer, and an intermediate boundary layer to separate or separate the aspirin-containing first and pravastatin-containing layers to prevent or minimize the interaction between aspirin and pravastatin. Contains buffer. Also provided are methods of using such compositions to lower cholesterol levels and reduce the risk of myocardial infarction. |