abstract |
The present invention relates to providing the gene sequence of the major pollen allergen Phl p 4. The present invention also includes fragments having hypoallergenic effects, novel combinations of partial sequences and point mutants. New combinations and variants of recombinant DNA molecules and derived polypeptides, fragments, subsequences can be used for the treatment of pollen allergic diseases. Proteins produced by recombinant methods can be used for in vitro and in vivo diagnosis of pollen allergy. |