| abstract |
The present invention includes a novel method of protecting a subject against malaria. The methods of the present invention include inoculation with attenuated sporozoites, which include, among others, subcutaneous administration, intramuscular administration, intradermal administration, mucosal administration, submucosal administration, and dermal administration. It is not limited. The present application provides methods for immunizing humans and animals against one or more malaria-causing pathogens. The method comprises the steps of eliciting an immune response in a human or animal by administering an initial vaccine of attenuated sporozoites to provide full or partial protective immunity against parasites of infectious Plasmodium species. Include. |