| abstract |
The present invention provides compositions and methods for inhibiting the growth or proliferation of hyperproliferating cells or inducing regression of hyperproliferating cells. More particularly, the present invention provides compositions and methods for stimulating glycogen accumulation in target cells (eg, hyperproliferating cells) to increase glycogen to levels that are toxic to the target cells. In one aspect, the present invention provides a method for increasing glycogen in a cell to a toxic level, the method comprising expressing in the cell a gene product that increases the amount of glycogen in the cell to a toxic level. . |