abstract |
The present invention relates to compositions containing excipients or solubilizers for proteins. The present invention relates to the discovery that peptides derived from the N-terminal extension of the T266 isoform of rhBMP2 have properties that enhance protein solubility. The present invention also relates to a method for resolubilizing a precipitated protein by contacting the protein with a peptide composed of a 17 amino acid extension of the T266 isoform of rhBMP-2. The present invention also relates to a method for enhancing protein solubility by contacting the protein with a peptide composed of a 17 amino acid extension of the T266 isoform of rhBMP-2. |