| abstract |
Formula (I): [Chemical 1] (Wherein D, Ar 1 , E and Ar 2 are as defined in the specification), nicotinic acetylcholine receptor, its enantiomer, pharmaceutically acceptable salt, process for its production, and pharmaceutical composition containing it As well as mental disorders, intellectual deficits, Alzheimer's disease, learning deficits, cognitive deficits, attention deficits, memory loss, Lewy body dementia, attention deficit hyperactivity injuries, anxiety, schizophrenia, mania or manic depression, To treat or prevent Parkinson's disease, Huntington's disease, Tourette's syndrome, neurodegenerative disorders with loss of cholinergic synapses, jet lag, smoking cessation, nicotine addiction, pain, ulcerative colitis or irritable bowel syndrome How to use it. |