abstract |
A plurality of novel diphenylethylene compounds comprising a plurality of thiazolidienedione or oxazolidinedione components effective in lowering blood glucose levels, serum insulin, triglycerides and free fatty acids in a plurality of animal models of type II diabetes Multiple derivatives are provided. As these compounds are useful for a variety of treatments including inflammation, multiple inflammatory and immune diseases, insulin resistance, hyperlipidemia, cardiac coronary artery disease, cancer and multiple sclerosis Disclosed. |