| abstract |
PROBLEM TO BE SOLVED: To perform a test using a conventional multilayer concave body incorporating apparatus, it is necessary to stain or fluorescently label cells, which adds an extra step and extra cost to the experiment. It was. The present invention generally relates to a multilayer concave body incorporating apparatus 100a including an upper test tank 114, a lower test tank 116, a membrane 106, and a sensor 120, and a method of using the same. The sensor 120 described above label-free an object 122 (eg, cell, molecule, protein, drug, compound, nucleic acid, peptide, carbohydrate) that has passed from the upper test tank 114 through the membrane 106 to the lower test tank 116. This is performed by measuring a change in the refractive index caused by the above-described object 122 existing on the surface 112 of the lower test chamber 116. |