abstract |
The present invention relates to pyrazole derivatives of formula (I) and their pharmaceutically acceptable salts, solvates or derivatives, their use in medicine, compositions containing them, processes for their preparation, and such processes. It relates to the intermediate used. The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, particularly inhibitors. Reverse transcriptase is related to the life cycle of human immunodeficiency virus (HIV) infection. Compounds that interfere with the function of this enzyme have shown utility in treating conditions such as acquired immune deficiency syndrome (AIDS) caused by HIV and gene-related retroviruses. |