abstract |
The present invention relates to a compound of formula (I): [Chemical 1] [Wherein L, X, Y, Z 1 , Z 2 , R 1 , R 2 , R 3 and G 2 have the meanings defined herein] A method for producing them; a medicinal composition containing them; a method for producing the medicinal composition; and their therapeutic use. The compounds of the present invention are inhibitors of metalloproteinase MMP12 and are particularly useful for the treatment of obstructive airway diseases such as asthma and chronic obstructive pulmonary disease (COPD). |