| abstract |
The pharmaceutical composition comprises one or more separate, orally deliverable dosage forms, each of which is an effective amount of poorly soluble when administered once daily for the treatment or prevention of COX-2 mediated disorders. A coxib component, an aspirin component in an amount effective for cardioprotection when administered once daily, and at least one pharmaceutically acceptable excipient; the dosage form comprises a substance for an intimate mixture of the coxib and aspirin component Have no physical obstacles. At the same time, a method of treating or preventing a COX-2 mediated disorder and providing cardioprotection comprises orally administering the pharmaceutical composition to a patient in need thereof. |