| abstract |
A non-toxic NMDA receptor antagonist is present in an amount that enhances the action of an analgesic, thereby reducing the amount of analgesic required to obtain the same action, but a non-toxic NMDA receptor antagonist Providing an analgesic composition comprising an analgesic in combination with a non-toxic NMDA receptor antagonist that is not present in an amount that exhibits adverse side effects. The method comprises a sustained release form of at least one analgesic in combination with an immediate release form of at least one non-toxic N-methyl-D-aspartate receptor antagonist in an amount that enhances analgesia. An analgesic composition. |