http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006340610-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
| filingDate | 2005-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f1dc13ac06f0fc2c2c3db7bafe62788 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c8983214fa5e61e07b294d4e5b88e40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78f3718a2028dfac84af9f8bb29b0c03 |
| publicationDate | 2006-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2006340610-A |
| titleOfInvention | Drug transport transporter substrate transport ability inhibition test method |
| abstract | 【Task】 Drug transport transporter (hereinafter referred to as TP) of chemical substances In the evaluation of inhibition of substrate transport ability, depending on the type of TP, sufficient evaluation results are not always obtained, and more accurate evaluation results are obtained. There was a need for a test method. [Solution] First step of setting the number of TP substrate concentrations in the cell to match the number of Km values of TP, and measuring the degree of inhibition of the TP substrate transport ability in the cells in the presence of the test compound for each concentration of the substrate Inhibiting test method of TP substrate transport ability having a plurality of Km values in cells possessed by test compound having second step, and each Km value based on degree of inhibition by concentration measured in said second step A method for evaluating the inhibitory ability of a test compound at a reaction site in the TP, which has a third step of evaluating the inhibitory ability of the test compound at a reaction site corresponding to 1. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5830085-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8945865-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012121261-A1 |
| priorityDate | 2005-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.