http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006298838-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_67f2bb9a79bd8433343ae221f81551cf |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04 |
| filingDate | 2005-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b63d4f3131319a63179d91957bfff997 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7a4ee5c2ba0702e5f467bc1f66afa4f |
| publicationDate | 2006-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2006298838-A |
| titleOfInvention | Liposome-containing X-ray contrast medium |
| abstract | 【Task】 To provide an X-ray contrast agent having excellent imaging ability and high safety. [Solution] The X-ray contrast agent of the present invention is produced by a supercritical carbon dioxide method that does not use any organic solvent containing ethanol, and contains a water-soluble nonionic iodine-based compound as a contrast medium in the aqueous phase inside and outside the lipid membrane, and physiological Contrast medium comprising liposomes containing a pharmaceutically acceptable formulation aid. The lipid membrane of the liposome is a liposome containing at least phospholipid, a lipid having a polyethylene glycol group and sterols as constituent components, having an average particle size of 0.05 to 0.8 μm, and the lipid membrane is 2 to 10 membranes The liposome composed of at least 80% comprises 100 to 250 mg I / mL contrast medium with the iodine compound as an iodine atom, and 60 to 150 mg / mL of total lipid. It contains by the density | concentration of a contrast agent. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9275029-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10489503-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5370153-B2 |
| priorityDate | 2005-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.