| abstract |
The present invention suppresses melanosome uptake in keratinocytes by having serine protease, especially trypsin activity inhibitory action. Thereby, the cosmetics with a high whitening effect are provided by using together the skin external preparation which suppresses discharge | emission to the epidermis of the melanin produced by the melanocyte, and has a whitening effect, and a melanin production inhibitor. SOLUTION: Liliaceae, Leek, Leguminous, Clara, Kudu, Soybean, Fuji, Forenum graekum, Cucurbitaceae, Pumpkin genus, Nigori, Loofah, Hemophila, Ceramaceae Serine protease inhibitor containing one or more compounds selected from the genus, Brassicaceae Alba, and melanin production inhibitor selected from ascorbic acid and its derivatives, arbutin and its derivatives Provide whitening cosmetics. |