Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05c62f2cf821f016678afe25fbcd6ced |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2005-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4e83285d2d219687b4a1785b42352e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54d8c14e57c197cc68900dbaaf493adc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c71422612eba4e7c722837bbf3d0b69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97b867e816f7a78e08013422ae935bba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a4fc42ded007cac83256d9a5b45797b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8346ace31567cd1bc9379095adb2e11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80bd757961d1f110fda4608a5f922bae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b4e814690551797095aaf40c31c9d28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c6afd03ab860f60633844d31b661f82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dc00a5aaa7838232f5fc3111f807e12 |
publicationDate |
2006-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2006217859-A |
titleOfInvention |
Method for screening therapeutic or preventive agent for Alzheimer's disease, method for diagnosing Alzheimer's disease, and method for predicting the risk of developing Alzheimer's disease |
abstract |
An object of the present invention is to provide a screening method effective for exploring therapeutic agents and preventive agents for Alzheimer's disease, and to provide an effective method for diagnosing Alzheimer's disease and predicting the onset of Alzheimer's disease. Changes in autotaxin activity comprising measuring autotaxin activity in the presence of a test substance and assaying whether the test substance changes or decreases autotaxin activity A screening method for a test substance to be reduced or reduced. A substance to be tested that reduces the activity of autotaxin is a therapeutic or preventive drug for Alzheimer's disease or a candidate substance thereof. A method of diagnosing Alzheimer's disease or predicting the risk of developing Alzheimer's disease by measuring the amount of autotaxin contained in a body fluid of a subject. A method for diagnosing Alzheimer's disease or predicting the risk of developing Alzheimer's disease by measuring the amount of lysophosphatidic acid contained in a body fluid of a subject. [Selection figure] None |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012002588-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009162616-A |
priorityDate |
2005-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |