| abstract |
The present invention provides a novel 2-aminopropane-1,3-diol compound which is excellent in immunosuppressive action, rejection inhibitory action and the like and has reduced side effects such as bradycardia. The general formula (I) [Chemical 1] (Wherein R 1 represents hydrogen or P (═O) (OH) 2 , R 2 represents cycloalkyl having 5 to 6 carbon atoms, and n represents an integer of 3 to 5). A pharmaceutical composition comprising an aminopropane-1,3-diol compound, a pharmaceutically acceptable acid addition salt thereof, or a hydrate and solvate thereof; the compound and a pharmaceutically acceptable carrier. [Selection figure] None |