| abstract |
PROBLEM TO BE SOLVED: To provide a production method capable of efficiently obtaining an optically active β-hydroxyamino acid derivative with high quality. An optical compound represented by the following general formula (2), wherein a β-ketoamino acid derivative represented by the following general formula (1) is asymmetrically reduced using a specific ruthenium-optically active phosphine complex. A method for producing an active β-hydroxyamino acid derivative. (Wherein R1 represents an alkyl group which may have a substituent, etc., R2 represents a hydrogen atom, an alkyl group, etc., and R3 represents a hydrogen atom, an alkyl group, etc.) (In the formula, R1, R2 and R3 have the same definitions as above, and * represents an asymmetric carbon.) [Selection figure] None |