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filingDate 2006-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0315071c654a75c160e7e01c74c1a06c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32a6b14ad635889fc168f7a3e2d6a10f
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publicationDate 2006-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2006204308-A
titleOfInvention Screening assays for agents that alter apoptosis inhibitor (IAP) protein regulation of caspase activity
abstract PROBLEM TO BE SOLVED To provide modulation of a member of a caspase family of cell death proteases by an apoptosis inhibitor (IAP) protein. A method for identifying an agent that modulates the caspase inhibitory activity of an apoptosis inhibitor (IAP) protein, the method comprising the following steps: (A) contacting the caspase and the IAP and an agent presumed to be able to modulate the caspase inhibitory activity of the IAP in vitro, wherein the IAP inhibits the caspase activity And (b) detecting caspase activity, wherein the caspase activity identifies an agent that modulates the caspase inhibitory activity of the IAP, Including the method. [Selection figure] None
priorityDate 1997-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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