| abstract |
Provided are diagnostic and therapeutic methods useful in various cancers such as human prostate cancer. STEAP encoding six prostatic transmembrane epithelial antigens (STEAP) of the novel family of cell surface serpentine transmembrane antigens expressed exclusively or predominantly in prostate as well as prostate cancer A STEAP protein and a polypeptide fragment thereof are prepared by a gene recombination technique using a gene or a complementary polynucleotide, and an antibody that binds to them is prepared. [Selection figure] None |