abstract |
【Task】 To provide a novel compound having a useful CXCR4 antagonistic action. [Solution] Compounds represented by general formula (I), salts thereof, solvates or prodrugs thereof, and pharmaceutical uses thereof (the symbols in the formula are as described in the specification). [Chemical 1] Since the compound represented by the general formula (I) has CXCR4 antagonism, CXCR4-mediated diseases such as inflammatory / immune diseases (for example, rheumatoid arthritis, arthritis, pulmonary fibrosis, transplanted organ rejection, etc.), allergy Diseases, infectious diseases (eg, human immunodeficiency virus infection, acquired immune deficiency syndrome, etc.), psychiatric / neurological diseases, brain diseases, cardiovascular diseases, metabolic diseases, cancer diseases (eg, cancer, cancer metastasis) It is useful as a preventive and / or therapeutic agent or the like for regenerative medicine. [Selection figure] None |