| abstract |
PROBLEM TO BE SOLVED: To find a gene whose expression is induced by β-amyloid and a protein encoded by the gene, a method for identifying a compound that inhibits the function of the protein and / or the expression of the gene, the function of the protein and / or the protein Provided are a pharmaceutical composition that can be used for diseases based on abnormal gene expression, and a diagnostic reagent kit for the diseases. A polynucleotide represented by a base sequence consisting of a specific sequence, a protein encoded by the polynucleotide, a vector containing the polynucleotide, a transformant containing the vector, an antibody against the protein, and the use thereof And a method for identifying a compound that inhibits the function of the protein and / or the expression of the gene, a method for diagnosing the disease, and a pharmaceutical composition and a reagent kit comprising them. [Selection figure] None |