| abstract |
[Solution] An amide derivative represented by the following formula (1) or a pharmaceutically acceptable salt thereof, or a hydrate or solvate thereof. [Chemical 1] [The symbols in the formula are the same as those described in the specification. ] 【effect】 The compound represented by the formula (1), or a pharmaceutically acceptable salt thereof, or a hydrate or solvate thereof has a C5a receptor antagonistic action and is a prophylactic agent for a disease involving C5a and / or It is useful as a therapeutic agent or anti-inflammatory agent, and further useful as a prophylactic and / or therapeutic agent for infectious diseases caused by bacteria or viruses that enter via the C5a receptor. |