| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8de5520d67b0ce661a2b197ee7f24b57 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-0072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6845
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B50-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-04 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04 |
| filingDate |
2005-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb38cf96378a33e2d6769ceef92f0162
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7000931655905450abbf360b96c1b91f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f8fc9443296a7ba79af566b0e0b5457
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_082d1a966427cced8fbf302ec4daa868 |
| publicationDate |
2006-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2006113077-A |
| titleOfInvention |
Extended tethering approach for rapid identification of ligands |
| abstract |
PROBLEM TO BE SOLVED: To provide a method for rapid identification and characterization of a binding partner for a target molecule, and for providing a binding partner with improved binding affinity. [Solution] Process, (I) contacting a target molecule (TM) having a target first site and a second site with a plurality of first small organic ligand candidates, wherein the TM is a target first site or Including or modified to include a reactive nucleophile or electrophile near the first site, the candidate having a functional group reactive with the nucleophile or electrophile; (Ii) identifying a first ligand derived from the complex of (i); and (iii) designing a derivative of the first ligand identified in (ii) to produce a nucleophile or nucleophile on the TM. Providing a SME having a first functional group reactive with an electronic agent and a second functional group reactive with a second ligand having affinity for a second site of interest. . [Selection figure] None |
| priorityDate |
2000-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |