http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006101705-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d75d1a4caed60a9316608ed9c231546c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7b097bfd3f350ed27ffa53e1f114d1a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5017 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2004-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c3542a7acbcfe619eefe135385a7f07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_148a64be9590fe8909caa2a212b61735 |
| publicationDate | 2006-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2006101705-A |
| titleOfInvention | Intracellular micronucleus detection method |
| abstract | Since the method is complicated and there are differences among testers, it is difficult to standardize between test laboratories. In addition, when automatic measurement is assumed, there is a problem in quantification and reproducibility because it is not easy to distinguish between a nuclear region and a cytoplasmic region depending on the current staining method. Toxicity of a test substance is produced by fusing a gene encoding a single or a plurality of nuclear-related proteins and a gene encoding a fluorescent protein into a cultured cell to produce a mother cell expressed in the cell. Alternatively, by performing treatment for mutagenicity tests, performing limited excitation such that the micronucleus region emits fluorescence in a limited manner, and measuring the amount of fluorescence according to the nuclear-related protein component quantitatively. Provided is a method for detecting intracellular micronuclei, which enables detection in living cells without fixing the cells of interest. [Selection figure] None |
| priorityDate | 2004-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.