http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006096738-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bed3149a0d5d9b970624b514912819a6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-606 |
| filingDate | 2005-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf2a19ce87a1651af21067eba76b387c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44b3d0152da864c379c88931bdd78464 |
| publicationDate | 2006-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2006096738-A |
| titleOfInvention | Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as chemopreventive and therapeutic agents for colorectal cancer |
| abstract | 【Task】 To provide an ideal drug for chemoprevention of colorectal cancer, which is a drug with the following profile: 1) colon specific; 2) limited absorption-parent and metabolite Minimal absorption; 3) no systemic activity-once absorbed, metabolic inactivation converts the drug to an inactive form, thereby systemically affecting the kidney and GI system 4) Antioxidant properties—colon specific antioxidant activity further acts to reduce carcinogen burden; and 5) NSAID-like anti-inflammatory mechanisms—active metabolites are pro-inflammatory eicosanoids Although the pathway should be inhibited, eicosanoid inhibition that does not impair the basal maintenance pathway is preferred. [Solution] The following general formula: Use of a pharmaceutical composition comprising a 2-hydroxy-5-phenylazobenzoic acid derivative. |
| priorityDate | 1994-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.