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publicationDate 2006-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2006071300-A
titleOfInvention Biochemical substance detector
abstract PROBLEM TO BE SOLVED: To easily and quickly measure a biochemical sensor that does not use a label such as a fluorescent substance because it does not need to introduce a label into a sample. However, the conventional non-labeled sensor has a problem that the sensitivity is insufficient compared with the measurement method using the label, and the measurement accuracy is deteriorated in a sample that is not sufficiently purified. A molecule that selectively binds to a substance to be detected in a sample is vibrated, and the amount of the molecule to be detected is measured by measuring a change in a vibration state before and after the binding. As a result, the influence of impurities having different vibration states can be suppressed. In addition, by measuring lock-in of periodic signals due to molecular vibrations, it is possible to reduce 1 / f noise caused by adsorption / desorption of molecules on the surface of a solid and increase sensitivity. [Selection] Figure 1
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016148655-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019100990-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012107901-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015015898-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011508199-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010133927-A
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