| abstract |
The present invention provides a multifunctional starch excipient that exhibits an excellent compression profile, good disintegration and dissolution properties, and excellent flowability. A free flowing fluid in which most particles have both birefringent and non-birefringent portions and have a sedimentation volume of 1.5-9 ml / g, as well as a cold water solubility of 1-8%. A multi-functional starch excipient with an average particle size greater than 30 μm and a moisture content of 5-12% by weight, and a manual tablet press equipped with a standard concave punch of 1.11 cm And a method for producing a placebo tablet having a crush strength of at least 160 N and a disintegration time of 10 minutes or less from the composition with a compressive force of 13 kN. [Selection] Figure 2 |