| abstract |
A novel compound having excellent antitumor activity is provided. SOLUTION: General formula (1) [Wherein X and Y are a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group, an aryl or heteroaryl group which may have a substituent, a nitro group, a cyano group, -CZ3, -NR1R2 , -CO2R3, -S (O) n-R4, -NHC (O) R5, -C (O) NR6R7, -COR8, -CH2-OR9, -CH = CH-R10, -CH = CH-COOR11, and One or more atoms or substituents selected from -CH = CH-CONHR12; A represents a diamino having a linear, branched or cyclic alkylene chain having 2 to 10 carbon atoms between two nitrogen atoms 1 or 2 nitrogen atoms together with the alkylene chain may form a 4-7 membered alicyclic heterocyclic group; B represents a carbonyl group or a sulfonyl group; Represents an aryl or heteroaryl group which may have a substituent, or a benzyl group which may be substituted with a lower alkyl group at the α-position. ] The furyl pyrimidine derivative represented by these, or its salt. [Selection figure] None |