abstract |
Disclosed is a COX-2 activity inhibitor that selectively inhibits cyclooxygenase-2 (COX-2) activity with low side effects and high safety. The COX-2 activity inhibitor of the present invention contains astaxanthin and / or an ester thereof. The COX-2 activity inhibitor of the present invention is also useful for the treatment of various diseases involving COX-2. Since the COX-2 activity inhibitor of the present invention does not substantially inhibit COX-1 activity, there is little possibility of causing side effects due to inhibition of COX-1 activity, and inflammatory diseases, allergic diseases, thrombosis, brain It is very useful for the treatment of various diseases such as disorders, cancer, lifestyle-related diseases and cardiovascular diseases. [Selection figure] None |