| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36c8d227913b07f7178030370183db99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3ee394f9473e4d751f6b81b79afe9330 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
| filingDate |
2004-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5f83f0419bc3b8dbad5d5b21119a7a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de60799a9d14c71a45b4ef358415f9d4 |
| publicationDate |
2006-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2006001866-A |
| titleOfInvention |
Melanin production inhibitor |
| abstract |
[PROBLEMS] To promote melanin production in melanocytes is a major factor of stain formation. Accordingly, the present invention searches for a melanin production inhibitor that has tyrosinase activity inhibition and can be used as an active ingredient of a whitening agent, and provides a melanin production inhibitor using the substance. It has been reported that the amount of melanin produced decreases when intracellular lactic acid increases. As a method of increasing intracellular lactic acid, as a result of investigating glycolytic products in which the final product is lactic acid, glycolytic products significantly suppress melanin production in B16 melanoma cells. As a result, it was found that by using phospholipid in combination, it can be a melanin production inhibitor having a melanin production inhibitory effect and a percutaneous absorption promotion effect, and the present invention has been completed. [Selection] “None” |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8163939-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010235560-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008143796-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008094813-A |
| priorityDate |
2004-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |