| abstract |
The present invention provides a compound of formula (I) or a pharmaceutically acceptable derivative thereof. These compounds are inhibitors of protein kinases, particularly inhibitors of GSK3 mammalian protein kinases. The present invention relates to inhibitors of protein kinases, particularly glycogen synthase kinase-3 (GSK-3), which is a serine / threonine protein kinase. The present invention also includes compositions containing the inhibitors of the present invention and these compositions in various disorders (eg, diabetes, Alzheimer's disease, Huntington's disease, Parkinson's disease, multiple sclerosis (MS), stroke, nervous system Disorders and neurodegenerative disorders, and psychiatric disorders) are provided. |