http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005538756-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-434 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-416 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-915 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-06 |
| filingDate | 2003-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2005-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2005538756-A |
| titleOfInvention | Medical device comprising a protein-tyrosine kinase inhibitor for inhibiting restenosis |
| abstract | An implantable medical device having an anti-restenosis coating is disclosed. Specifically, an implantable medical device having a coating of a protein-tyrosine kinase inhibitor is disclosed. This anti-restenosis protein-tyrosine kinase inhibitor is 4-[(4-methyl-1-piperazinyl) methyl] -N- [4-methyl-3-[[4- (3-pyridinyl) -2-pyrimidinyl] Amino] phenyl] benzamide methanesulfonate, and pharmaceutically acceptable derivatives thereof (imatinib mesylate). The medical devices include stents, catheters, microparticles, probes, and vascular grafts. The medical device can be coated using methods known in the art including combining a protein-tyrosine kinase inhibitor with a biocompatible polymer prior to coating. Further disclosed are medical device compositions comprised of biocompatible polymer-protein-tyrosine kinase inhibitor blends. Further disclosed is a medical device having a coating comprising at least one protein-tyrosine kinase inhibitor together with at least one additional therapeutic agent. Furthermore, related methods of using and manufacturing anti-restenotic implantable medical devices are also disclosed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8349390-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008532692-A |
| priorityDate | 2002-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 185.