Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-124 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0647 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0692 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 |
filingDate |
2003-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2005-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2005538742-A |
titleOfInvention |
Hematopoietic stem cells and methods of treating neovascular diseases of the eye using the cells |
abstract |
An isolated, mammalian, bone marrow-derived, lineage-negative hematopoietic stem cell population (Lin - HSC) contains endothelial progenitor cells (EPCs) capable of forming retinal blood vessels. At least about 50% of the cells of the isolated Lin HSC population have CD31 and c-kit cell surface markers. Up to about 8% of cells can have a Sca-1 cell marker and up to about 4% of cells can have a Flk-1 / KDR marker. The isolated Lin HSC population of the present invention is useful for treating ocular vascular disease. Also provided is an isolated Lin HSC population transfected with a therapeutically useful gene, which is useful for delivering genes to the eye in cell-based gene therapy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006166918-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4714580-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4714682-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006525806-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2014030749-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014030749-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150047538-A |
priorityDate |
2002-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |