| abstract |
The present invention relates to alkanal derivatives of water-soluble polymers such as, for example, poly (ethylene glycol), their corresponding hydrates and acetals, and methods for preparing and using such polymer alkanals. The polymeric alkanals of the present invention are prepared with high purity and exhibit storage stability. Certain polymeric aldehydes described herein are more stable at basic pH than known aldehyde derivatives of the prior art and form large or detectable amounts of reverse Michael-type reaction byproducts. Formed without. |