Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate |
2002-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2005-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2005536986-A |
titleOfInvention |
C5a anaphylatoxin muteins, nucleic acid molecules encoding such muteins and pharmaceutical uses of C5a anaphylatoxin muteins |
abstract |
The present invention relates to a C5a anaphylatoxin (C5a) mutein, a C5a receptor antagonist, a nucleic acid molecule comprising a nucleotide sequence encoding such a mutated protein of C5a anaphylatoxin. Reference is made to a pharmaceutical composition comprising a mutein of a C5a anaphylatoxin that acts as a C5a receptor antagonist, as well as a host cell containing a nucleic acid molecule comprising a nucleotide sequence encoding such a mutein. The mutein of the present invention is a C5a receptor antagonist in which a naturally occurring amino acid residue is mutated at sequence position 69. |
priorityDate |
2002-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |