http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005536748-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D219-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D219-04 |
| filingDate | 2003-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2005-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2005536748-A |
| titleOfInvention | Hydrophilic chemiluminescent acridinium labeling agent |
| abstract | According to the present invention, by introducing a hydrophilic sulfoalkyl substituent and / or a hydrophilic linker derived from homocysteic acid, cysteic acid, glycine peptide, tetraethylene oxide, etc., the hydrophobicity of the acridinium ring system is offset, It has been found that a more soluble label can be produced that can bind to the antibody in a high volume before precipitation or aggregation problems occur. Additional compounds described herein include short peptides and tetraethylene oxide derived linkers that increase water solubility through hydrogen bonding with water molecules. The present invention also provides a plurality of acridinium labeling agents for signal amplification consisting of a peptide carrying several acridinium esters having sulfonic acid groups at regular intervals to increase solubility. Include. The present invention also encompasses assay methods using the compounds described above. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9575062-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008216046-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007315779-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009143821-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013510934-A |
| priorityDate | 2002-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.