| abstract |
The embodiments of the invention described herein relate to antibodies against antigen monocyte chemotactic protein-1 (MCP-1) and the use of such antibodies. In particular, according to some embodiments, a fully human monoclonal antibody directed to the antigen MCP-1 is provided. Nucleotide sequences encoding heavy and light chain immunoglobulin molecules, and amino acid sequences containing those molecules, particularly framework regions and / or complementarity determining regions (CDRs), specifically FR1 to FR4 or CDR1 to CDR3 Providing sequences corresponding to the extended heavy and light chain sequences. Hybridomas or other cell lines that express such immunoglobulin molecules and monoclonal antibodies are also provided. |