| abstract |
The present invention refers to (a) Formula I, wherein M represents a macrolide subunit (macrolide moiety) derived from a macrolide that retains the properties of accumulating in inflammatory cells, D represents anti-inflammatory, analgesic, and / Or represents a non-steroidal subunit (non-steroidal moiety) derived from a non-steroidal drug having antipyretic activity (NSAID), and L represents a bridging group that covalently links M and D] Compounds, (b) pharmacologically acceptable salts, prodrugs and solvates thereof, (c) methods for their preparation and intermediate products, and (d) treating human and animal inflammatory diseases and conditions Related to its use. |