| abstract |
The present invention is porcine animals, porcine tissues, porcine cells, and porcine cell lines that lack any expression of functional α-1,3-galactosyltransferase (α1,3GT). These animals, tissues, organs, and cells can be used in xenotransplantation. These animals, tissues, organs, and cells can be used for other medical purposes. The present invention relates to porcine animals, porcine tissues, and porcine organs, and cells and cell lines derived from such animals, tissues, and organs, which are any of the functional α-1,3-galactosyltransferases. It also lacks expression. Such animals, tissues, organs, and cells can be used in research and medical therapy (including xenografts). |