| abstract |
PROBLEM TO BE SOLVED: To disclose a multi-modality fluorescence reference plate having wells coated with a fluorescence generating compound and a method for producing the same. The multi-modality fluorescent reference plate of the present invention comprises one or more wells, each well having a base, the base of the one or more wells comprising a coating of a fluorogenic compound. The reference plate can be used to calibrate a fluorescence plate reader and imaging system for measurement of steady state fluorescence, time resolved fluorescence, fluorescence lifetime and / or fluorescence polarization. |