| abstract |
2 'and / or 3' prodrugs of 1 ', 2', 3 'or 4'-branched nucleosides and their pharmaceutically acceptable salts and derivatives are described. These prodrugs are useful in the prevention and treatment of flaviviridae viral infections such as HCV infection and other related conditions. The prodrug compounds and compositions of the invention are described. Also provided are methods and uses having the step of administering an effective amount of a prodrug of the present invention or a pharmaceutically acceptable salt or derivative thereof. These agents may be administered in combination or alternate administration with another antiviral agent to prevent or treat flaviviridae viral infections and other related conditions. |