http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005533510-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2537-143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6813 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00 |
filingDate | 2003-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2005-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2005533510-A |
titleOfInvention | NOVEL ANALYSIS METHOD OF NUCLEIC ACID AND USE THEREOF TO EVALUATE THE EDITING LEVEL OF mRNA, Especially Serotonin 5-HT2C Receptor mRNA |
abstract | The present invention relates to a method for analyzing nucleic acids using a small size probe sequence comprising deoxyinosine (dI) instead of deoxyguanosine (dG). The present invention relates to such probe sequences and their use in methods for detecting and / or quantifying target oligonucleotides present in DNA (deoxyribonucleic acid) or RNA (ribonucleic acid) molecules in a sample, in particular serotonin 5- It also relates to the mRNA editing rate of the HT 2C receptor (5-HT 2C -R). The present invention is capable of detecting and / or identifying, or 5-HT 2C- R mRNA or editing biochips or reactors in liquid media comprising such probe sequences, and in particular genetic polymorphisms. It also relates to their use to determine the mRNA editing rate regardless of the editing rate of any other RNA. The present invention relates to a method based on the isolation of single-stranded conformational polymorphism (SSCP) that can obtain the editing profile and / or rate of mRNA that can be edited under special analytical conditions, and mRNA. It also relates to a method for diagnosing a disease or susceptibility to a disease associated with the degree of editing. Finally, the present invention relates to a method for selecting a compound capable of adjusting the mRNA editing rate, in particular the editing rate of 5-HT 2C -R, as well as for producing a pharmaceutical composition for treating organic fluids. It relates to the use of the above compounds. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010528672-A |
priorityDate | 2002-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.