http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005533094-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C311-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C311-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 |
| filingDate | 2003-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2005-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2005533094-A |
| titleOfInvention | Method for separating R (-)-and S (+)-5- [2-[[2- (2-ethoxyphenoxy) ethyl] amino] propyl] -2-methoxybenzenesulfonamide |
| abstract | A process for separating R (−)-I and S (+)-5- [2-[[2- (2-ethoxyphenoxy) ethyl] amino] propyl] -2-methoxybenzenesulfonamide, comprising: (A) reacting the mixture of enantiomers with an optically active organic acid to form a diastereoisomeric salt having the enantiomer that has different solubilities and can be separated by crystallization; and (b) ) Separating the diastereomeric salt mixture concentrated in one salt of the enantiomer; and (c) releasing the salt to obtain the R (−) or S (+) enantiomer. Comprising. R (−)-5- [2-[[2- (2-Ethoxyphenoxy) ethyl] amino] propyl] -2-methoxybenzenesulfonamide enantiomer has α-adrenergic blocking activity and is congestive It is useful as an antihypertensive drug suitable for the treatment of congenital heart failure and benign prostatic hypertrophy. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012505183-A |
| priorityDate | 2002-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.