| abstract |
The present invention provides methods and compositions for treating and repairing ligament defects using bone morphogenetic proteins. The present invention provides for the treatment of ligament defects, repair of ligament defects, formation of ligament tissue, regeneration of ligament tissue, and promotion of ligament tissue growth by transplanting ligament cells cultured ex vivo. Provide a way to do them. The method of the present invention includes the following steps. That is, (a) a step of separating ligament cells, (b) a step of culturing the ligament cells ex vivo, (c) a step of recovering the cultured ligament cells, and (d) a recovered ligament cell. Transplanting to a patient. |