| abstract |
The present invention relates to azole derivatives, particularly for use as pharmaceutically active compounds, as well as pharmaceutical formulations containing such azole derivatives. Said azole derivatives are modulators of protein kinase signaling pathways, in particular those involving c-Jun N-terminal kinase and / or glycogen kinase synthase 3. The invention further relates to novel azole derivatives and also to a process for their preparation. X is O, S or NR 0 , R 0 is H or unsubstituted or substituted C 1 -C 6 alkyl; A is 2-pyridyl, 3-pyridyl, 4-pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl Or a triazinyl group. [Chemical 1] |